发明公开
- 专利标题： TARGETED DELIVERY OF RETINOID COMPOUNDS TO THE SEBACEOUS GLANDS
- 专利标题（中）： TO皮脂腺类视黄醇的连接靶向释放
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申请号： EP12728145.9申请日： 2012-06-01
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公开(公告)号： EP2714016A1公开(公告)日： 2014-04-09
- 发明人: DONELLO, John, E. , YANG, Rong
- 申请人： Allergan, Inc.
- 申请人地址： 2525 Dupont Drive Irvine, CA 92612 US
- 专利权人： Allergan, Inc.
- 当前专利权人： Allergan, Inc.
- 当前专利权人地址： 2525 Dupont Drive Irvine, CA 92612 US
- 代理机构： HOFFMANN EITLE
- 优先权： US201161493341P 20110603
- 国际公布： WO2012167018 20121206
- 主分类号： A61K9/50
- IPC分类号： A61K9/50 ; A61K9/00 ; A61K31/4436 ; A61P17/08 ; A61P17/10
摘要：
Disclosed herein are topical dermal compositions comprising particles, wherein the particles comprise a) a biodegradable polymer, and b) a retinoid selected from the group consisting of: (I) and (II), or a pharmaceutically acceptable salt thereof, wherein the particles have an average diameter between 0.1 μιτι and 10 μιτι, and wherein the variables are as defined in the specification. The compositions are useful for treating a condition associated with excess sebum production.
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