发明公开
EP2714036A4 SUBSITUTED ALIPHANES, CYCLOPHANES, HETERAPHANES, HETEROPHANES, HETERO-HETERAPHANES AND METALLOCENES USEFUL FOR TREATING HCV INFECTIONS
有权
取代ALIPHANE类，环，HETERAPHANE，HETEROPHANE，杂HETERAPHANE金属茂和丙型肝炎病毒感染的治疗
- 专利标题： SUBSITUTED ALIPHANES, CYCLOPHANES, HETERAPHANES, HETEROPHANES, HETERO-HETERAPHANES AND METALLOCENES USEFUL FOR TREATING HCV INFECTIONS
- 专利标题（中）： 取代ALIPHANE类，环，HETERAPHANE，HETEROPHANE，杂HETERAPHANE金属茂和丙型肝炎病毒感染的治疗
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申请号： EP12793566申请日： 2012-05-29
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公开(公告)号： EP2714036A4公开(公告)日： 2014-11-12
- 发明人: WILES JASON ALLAN , WANG QIUPING , HASHIMOTO AKIHIRO , PAIS GODWIN , CHEN DAWEI , WANG XIANGZHU , GADHACHANDA VENKAT , PHADKE AVINASH , DESHPANDE MILIND
- 申请人： ACHILLION PHARMACEUTICALS INC
- 专利权人： ACHILLION PHARMACEUTICALS INC
- 当前专利权人： ACHILLION PHARMACEUTICALS INC
- 优先权： US201161490881 2011-05-27; US201161504905 2011-07-06; US201161567216 2011-12-06
- 主分类号： C07F17/02
- IPC分类号： C07F17/02 ; A61K31/4164 ; A61K31/4178 ; A61P31/00 ; A61P31/12 ; C07D401/14 ; C07D403/14 ; C07D413/14 ; C07D417/14 ; C07D471/08 ; C07D471/14 ; C07D491/10 ; C07D519/00
摘要：
Provided is a compound having a structure selected from the group consisting of: which are intermediates in the preparation of Carbamic acid, N,N'-[tricyclo[8.2.2.24,7]hexadeca-4,6,10,12,13,15-hexaene-5,11-diyl bis [1H-benzimidazole-6,2-diyl[(2S,3aS,7aS)-octahydro-1H-indole-2,1-diyl][(1S)-1-(1-methylethyl)-2-oxo-2,1-ethane diyl]]] bis-, C,C'-dimethyl ester, which is a Hepatitis C virus NS5a (HCV NS5a) protease replication inhibitor
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