发明公开
EP2714933A2 METHODS USING DNA METHYLATION FOR IDENTIFYING A CELL OR A MIXTURE OF CELLS FOR PROGNOSIS AND DIAGNOSIS OF DISEASES, AND FOR CELL REMEDIATION THERAPIES
审中-公开
与DNA甲基化过程用于识别细胞疗法的细胞或疾病的细胞的混合物预测和诊断和治疗
- 专利标题： METHODS USING DNA METHYLATION FOR IDENTIFYING A CELL OR A MIXTURE OF CELLS FOR PROGNOSIS AND DIAGNOSIS OF DISEASES, AND FOR CELL REMEDIATION THERAPIES
- 专利标题（中）： 与DNA甲基化过程用于识别细胞疗法的细胞或疾病的细胞的混合物预测和诊断和治疗
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申请号： EP12789375.8申请日： 2012-05-25
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公开(公告)号： EP2714933A2公开(公告)日： 2014-04-09
- 发明人: KELSEY, Karl , HOUSEMAN, Eugene, Andres , WIENCKE, John , ACCOMANDO, William, P., Jr. , MARSIT, Carmen
- 申请人： Brown University , The Regents of The University of California
- 申请人地址： Horace Mann Building 47 George Street, Third Floor Providence, RI 02912 US
- 专利权人： Brown University,The Regents of The University of California
- 当前专利权人： Brown University,The Regents of The University of California
- 当前专利权人地址： Horace Mann Building 47 George Street, Third Floor Providence, RI 02912 US
- 代理机构： WP Thompson
- 优先权： US201161489883P 20110525; US201161509644P 20110720; US201261585892P 20120112; US201261619663P 20120403
- 国际公布： WO2012162660 20121129
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12N15/11 ; G06F17/10
摘要：
Methods using DNA Methylation arrays are provided for identifying a cell or mixture of cells and for quantification of alterations in distribution of cells in blood or in tissues, and for diagnosing, prognosing and treating disease conditions, particularly cancer. The methods use fresh and archival samples.
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