In a wireless communication device with multiple radio access technologies (RATs), frame timing for one RAT may be aligned with a frame timing of another RAT so as to reduce a number of communication frames of the different RATs that overlap in time with each other. The aligning reduces the number of communication frames that are subject to cancellation due to interference. Alignment may reduce a number of transmit frames of one RAT that overlap with multiple receive frames of another RAT. Alignment may reduce a number of receive frames of one RAT that overlap with multiple transmit frames of another RAT.