发明公开
EP2729161A2 FACTOR VIII CHIMERIC AND HYBRID POLYPEPTIDES, AND METHODS OF USE THEREOF
审中-公开
嵌合和杂合因子VIII多肽及其使用方法
- 专利标题： FACTOR VIII CHIMERIC AND HYBRID POLYPEPTIDES, AND METHODS OF USE THEREOF
- 专利标题（中）： 嵌合和杂合因子VIII多肽及其使用方法
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申请号： EP12811808.0申请日： 2012-07-06
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公开(公告)号： EP2729161A2公开(公告)日： 2014-05-14
- 发明人: DUMONT, Jennifer A. , LOW, Susan , BITONTI, Alan, J. , PIERCE, Glenn , LUK, Alvin , JIANG, Haiyan , MCKINNEY, Byron , OTTMER, Matt , SOMMER, Jurg , NUGENT, Karen , LI, Lian , PETERS, Robert
- 申请人： BIOGEN IDEC HEMOPHILIA INC.
- 申请人地址： 9 Fourth Avenue Waltham, MA 02451 US
- 专利权人： BIOGEN IDEC HEMOPHILIA INC.
- 当前专利权人： BIOGEN IDEC HEMOPHILIA INC.
- 当前专利权人地址： 9 Fourth Avenue Waltham, MA 02451 US
- 代理机构： Miller, David James
- 优先权： US201161506015P 20110708; US201161522647P 20110811; US201161541561P 20110930; US201161569158P 20111209; US201261586443P 20120113; US201261622789P 20120411; US201261657641P 20120608
- 国际公布： WO2013009627 20130117
- 主分类号： A61K38/37
- IPC分类号： A61K38/37 ; C07K14/755
摘要：
The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.
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