- 专利标题： INHIBITORS OF BRUTON'S TYROSINE KINASE
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申请号： EP12811600.1申请日： 2012-07-13
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公开(公告)号： EP2731612A2公开(公告)日： 2014-05-21
- 发明人: CHEN, Wei , LOURY, David, J. , MODY, Tarak, D. , WANG, Longcheng
- 申请人： Pharmacyclics, Inc.
- 申请人地址： 995 East Arques Avenue Sunnyvale, CA 94085 US
- 专利权人： Pharmacyclics, Inc.
- 当前专利权人： Pharmacyclics, Inc.
- 当前专利权人地址： 995 East Arques Avenue Sunnyvale, CA 94085 US
- 代理机构： Harrison Goddard Foote LLP
- 优先权： US201161507482P 20110713
- 国际公布： WO2013010136 20130117
- 主分类号： A61K31/52
- IPC分类号： A61K31/52 ; A61K31/433 ; C07D473/34 ; C07D473/32 ; A61P17/00 ; A61P29/00
摘要：
Described herein are kinase inhibitor compounds, methods for synthesizing such inhibitors, and methods for using such inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate inhibitor of a protein, including a kinase.
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