发明公开
EP2732277A1 NON COVALENT MOLECULAR STRUCTURE, COMPRISING A PYRENE BASED GLYCOCONJUGATE, DEVICE COMPRISING THE SAME AND ITS USE FOR DETECTION OF LECTIN
审中-公开
基于凝集素的检测的糖缀合物，装置及正确使用芘衍生物NOT COVALENT分子结构
- 专利标题： NON COVALENT MOLECULAR STRUCTURE, COMPRISING A PYRENE BASED GLYCOCONJUGATE, DEVICE COMPRISING THE SAME AND ITS USE FOR DETECTION OF LECTIN
- 专利标题（中）： 基于凝集素的检测的糖缀合物，装置及正确使用芘衍生物NOT COVALENT分子结构
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申请号： EP11748726.4申请日： 2011-07-12
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公开(公告)号： EP2732277A1公开(公告)日： 2014-05-21
- 发明人: STAR, Alexander , VIDAL, Sébastien , IMBERTY, Anne
- 申请人： Centre National de la Recherche Scientifique (CNRS) , Université Claude Bernard Lyon 1 (UCBL) , INSA Lyon , University of Pittsburgh - Of The Commonwealth System of Higher Education
- 申请人地址： 3, rue Michel-Ange 75794 Paris Cedex 16 FR
- 专利权人： Centre National de la Recherche Scientifique (CNRS),Université Claude Bernard Lyon 1 (UCBL),INSA Lyon,University of Pittsburgh - Of The Commonwealth System of Higher Education
- 当前专利权人： Centre National de la Recherche Scientifique (CNRS),Université Claude Bernard Lyon 1 (UCBL),INSA Lyon,University of Pittsburgh - Of The Commonwealth System of Higher Education
- 当前专利权人地址： 3, rue Michel-Ange 75794 Paris Cedex 16 FR
- 代理机构： Peaucelle, Chantal
- 国际公布： WO2013008062 20130117
- 主分类号： G01N27/414
- IPC分类号： G01N27/414 ; B82Y5/00 ; G01N33/543 ; C07H15/26
摘要：
The present invention relates to a non covalent molecular structure comprising a carbon nanostructure and a pyrene based glycoconjugate (I) which is linked to the said carbon nanostructure by a non covalent link, the said glycoconjugate (I) having the formula : wherein B is a group which is present on any of the ten carbon atoms of the pyrene structure represented in ( I ) susceptible to bear a substituent, and is represented by the following group : -(CH2)
n -CO-NH-A, wherein n is an integer from 1 to 9, A is a group of formula : The present invention also relates to an electronic device comprising the said non covalent molecular structure, and to the use of this device for the detection of a lectin involved in bacterial or viral infections. Thus the invention also relates to a method for detecting the presence of a lectin in a sample to be analysed.
n -CO-NH-A, wherein n is an integer from 1 to 9, A is a group of formula : The present invention also relates to an electronic device comprising the said non covalent molecular structure, and to the use of this device for the detection of a lectin involved in bacterial or viral infections. Thus the invention also relates to a method for detecting the presence of a lectin in a sample to be analysed.
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