发明公开
- 专利标题： DENIBULIN DI-HYDROCHLORIDE
- 专利标题（中）： 德尼布林，二盐酸盐
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申请号： EP12820152.2申请日： 2012-07-27
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公开(公告)号： EP2736334A1公开(公告)日： 2014-06-04
- 发明人: RUBY, Kale
- 申请人： MediciNova, Inc.
- 申请人地址： 4350 La Jolla Village Drive Suite 950 San Diego, CA 92122 US
- 专利权人： MediciNova, Inc.
- 当前专利权人： MediciNova, Inc.
- 当前专利权人地址： 4350 La Jolla Village Drive Suite 950 San Diego, CA 92122 US
- 代理机构： Nederlandsch Octrooibureau
- 优先权： US201161457994P 20110729
- 国际公布： WO2013019611 20130207
- 主分类号： A01N43/40
- IPC分类号： A01N43/40
摘要：
MN-029 di-hydrochloride (MN-029.2HC1, Formula 2) is a potent vascular targeting agent. The present invention focuses on the synthesis and characterization of the di-hydrochloride salt MN-029 and the preparation of pharmaceutically acceptable formulations thereof. Methods are disclosed of using the compound and formulations thereof in the treatment of diseases that rely on the generation of neovasculature by angiogenesis for disease progression.
公开/授权文献
- EP2736334B1 DENIBULIN DI-HYDROCHLORIDE 公开/授权日：2016-06-01
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