发明公开
EP2744829A4 ANTIBODIES TO CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE (CEACAM)
有权
防静电手套GACEN DAS KARZINOEMBRYONISCHE ANTIGEN-ZELLADHÄSIONSMOLEKÜL（CEACAM）
- 专利标题： ANTIBODIES TO CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE (CEACAM)
- 专利标题（中）： 防静电手套GACEN DAS KARZINOEMBRYONISCHE ANTIGEN-ZELLADHÄSIONSMOLEKÜL（CEACAM）
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申请号： EP12840002申请日： 2012-10-10
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公开(公告)号： EP2744829A4公开(公告)日： 2015-06-03
- 发明人: MARKEL GAL , BEN MOSHE TEHILA , SAPIR YAIR , MANDEL ILANA , SCHACHTER JACOB , ORTENBERG RONA
- 申请人： TEL HASHOMER MEDICAL RES INFRASTRUCTURE & SERVICES LTD , CCAM BIOTHERAPEUTICS LTD , UNIV RAMOT
- 专利权人： TEL HASHOMER MEDICAL RES INFRASTRUCTURE & SERVICES LTD,CCAM BIOTHERAPEUTICS LTD,UNIV RAMOT
- 当前专利权人： TEL HASHOMER MEDICAL RES INFRASTRUCTURE & SERVICES LTD,CCAM BIOTHERAPEUTICS LTD,UNIV RAMOT
- 优先权： IL2011000808 2011-10-11
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K35/17 ; A61K39/00 ; A61K39/395 ; A61K45/06 ; A61P35/00 ; C07K16/30 ; C07K16/42 ; G01N33/53 ; G01N33/68
摘要：
The present invention provides antibodies, as well as molecules having at least the antigen-binding portion of an antibody, recognizing a specific epitope of the protein CEACAM1 and optionally binds also other subtypes of the CEACAM protein family. Disclosed antibodies and antibody fragments are characterized by specific CDR sequences. Methods of production and use in therapy and diagnosis, of such antibodies and antibody fragments are also provided.
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