- 专利标题： ISOLATION OF FACTORS THAT ASSOCIATE DIRECTLY OR INDIRECTLY WITH NON-CODING RNAS
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申请号： EP12825262.4申请日： 2012-08-20
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公开(公告)号： EP2744902B1公开(公告)日： 2018-06-06
- 发明人: KINGSTON, Robert , SIMON, Matthew , WEST, Jason Allen
- 申请人： The General Hospital Corporation
- 申请人地址： 55 Fruit Street Boston, MA 02114 US
- 专利权人： The General Hospital Corporation
- 当前专利权人： The General Hospital Corporation
- 当前专利权人地址： 55 Fruit Street Boston, MA 02114 US
- 代理机构： Moore, Michael Richard
- 优先权： US201161525559P 20110819
- 国际公布： WO2013028611 20130228
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C12Q1/68 ; G01N33/553
摘要：
Methods and assays are provided for isolating factors including polypeptides, ribonucleic acids (RNAs) and polypeptide complexes that are associated with a target nucleic acid sequence. The target nucleic acid sequence may be comprised within chromatin. The methods are suitable for identification and characterisation of factors including non-coding RNAs (ncRNAs) that associate with specified genomic loci.
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