发明公开
- 专利标题： USE OF A PROTEOLYTIC ENZYME
- 专利标题（中）： 使用蛋白水解酶
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申请号： EP12837914.6申请日： 2012-10-04
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公开(公告)号： EP2764092A1公开(公告)日： 2014-08-13
- 发明人: KERKELÄ, Erja , HAKKARAINEN, Tanja , NYSTEDT, Johanna , PARTANEN, Jukka
- 申请人： Glykos Finland Oy
- 申请人地址： Viikinkaari 6 00790 Helsinki FI
- 专利权人： Glykos Finland Oy
- 当前专利权人： Glykos Finland Oy
- 当前专利权人地址： Viikinkaari 6 00790 Helsinki FI
- 代理机构： Kolster Oy Ab
- 优先权： FI20115976 20111005
- 国际公布： WO2013050656 20130411
- 主分类号： C12N5/0789
- IPC分类号： C12N5/0789
摘要：
The present invention relates to a hematopoietic stem cell and/or a population thereof having a specific profile of cell surface proteins and/or proteoglycans. The present invention also relates to use of proteolytic enzymes, such as pronase and pronase-like enzymes in the modification of the cell surface of a hematopoietic stem cell. The present invention further relates to a method of modifying the cell surface of a hematopoietic stem cell by treatment with proteolytic enzymes, such as pronase and pronase-like enzymes.
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