发明公开
EP2773207A4 AMINOPYRIMIDINONES AS INTERLEUKIN RECEPTOR-ASSOCIATED KINASE INHIBITORS
有权
Aminopyrimidinones ALS白细胞介素相关激酶抑制剂
- 专利标题： AMINOPYRIMIDINONES AS INTERLEUKIN RECEPTOR-ASSOCIATED KINASE INHIBITORS
- 专利标题（中）： Aminopyrimidinones ALS白细胞介素相关激酶抑制剂
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申请号： EP12845873申请日： 2012-10-26
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公开(公告)号： EP2773207A4公开(公告)日： 2015-07-01
- 发明人: SEGANISH W MICHAEL , BRUMFIELD STEPHANIE NICOLE , LIM JONGWON , MATASI JULIUS J , MCELROY WILLIAM T , TULSHIAN DEEN B , LAVEY BRIAN J , ALTMAN MICHAEL D , GIBEAU CRAIG R , LAMPE JOHN WILLIAM , METHOT JOEY , ZHU LIANG
- 申请人： MERCK SHARP & DOHME
- 专利权人： MERCK SHARP & DOHME
- 当前专利权人： MERCK SHARP & DOHME
- 优先权： US201161553621 2011-10-31
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D401/04 ; C07D413/14 ; C07D417/04 ; C07D491/08 ; C07D491/10
摘要：
This invention relates to aminopyrimidinone compounds of Formula (I) that are inhibitors of Interleukin receptor-associated kinases, in particular IRAK-4, and are useful in the treatment or prevention of inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease.
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