发明授权
EP2780031B1 GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING GLUCOCORTICOID RECEPTOR ACTIVITY
有权
显示糖皮质激素受体活性的胰高血糖素肽
- 专利标题： GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING GLUCOCORTICOID RECEPTOR ACTIVITY
- 专利标题（中）： 显示糖皮质激素受体活性的胰高血糖素肽
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申请号： EP12849285.7申请日： 2012-11-16
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公开(公告)号： EP2780031B1公开(公告)日： 2018-03-07
- 发明人: DIMARCHI, Richard D. , YANG, Bin
- 申请人： Indiana University Research and Technology Corporation
- 申请人地址： 518 Indiana Avenue Indianapolis, IN 46202 US
- 专利权人： Indiana University Research and Technology Corporation
- 当前专利权人： Indiana University Research and Technology Corporation
- 当前专利权人地址： 518 Indiana Avenue Indianapolis, IN 46202 US
- 代理机构： Oficina Ponti, SLP
- 优先权： US201161561094P 20111117
- 国际公布： WO2013074910 20130523
- 主分类号： A61K38/26
- IPC分类号： A61K38/26 ; A61K38/00 ; A61K31/56
摘要：
Provided herein are glucagon superfamily peptides conjugated with GR ligands that are capable of acting at a glucocorticoid receptor. Also provided herein are pharmaceutical compositions and kits of the conjugates of the invention. Further provided herein are methods of treating a disease, e.g., a metabolic disorder, such as diabetes and obesity, comprising administering the conjugates of the invention.
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