发明公开
EP2781508A4 NITROGEN-CONTAINING FUSED RING COMPOUNDS FOR USE AS CRTH2 ANTAGONISTS
有权
含氮稠环化合物,其用作为CRTH2拮抗剂
- 专利标题: NITROGEN-CONTAINING FUSED RING COMPOUNDS FOR USE AS CRTH2 ANTAGONISTS
- 专利标题(中): 含氮稠环化合物,其用作为CRTH2拮抗剂
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申请号: EP12850344申请日: 2012-11-16
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公开(公告)号: EP2781508A4公开(公告)日: 2015-04-29
- 发明人: ZHANG YAN , ZHANG MIN , LO HOYIN
- 申请人: KBP BIOSCIENCES CO LTD
- 专利权人: KBP BIOSCIENCES CO LTD
- 当前专利权人: KBP BIOSCIENCES CO LTD
- 优先权: CN201110364581 2011-11-17; CN201210319955 2012-09-03
- 主分类号: C07D209/22
- IPC分类号: C07D209/22 ; A61K31/405 ; A61K31/416 ; A61K31/4162 ; A61P11/06 ; A61P37/00 ; C07D231/56 ; C07D403/06 ; C07D471/04
摘要:
The present application relates to nitrogen-containing fused ring compounds shown by general formula (I), a pharmaceutically acceptable salt thereof and a stereoisomer thereof as CRTH2 antagonist, wherein X 1 , X 2 , X 3 , X 4 , X 5 , W, X, Y, L 1 , L 2 , L 3 , A, B are as defined in the description; the present application further relates to a method for preparing the compounds, a pharmaceutical formulation and a pharmaceutical composition comprising the compounds, a use of the compounds for the manufacture of a medicament for the treatment and/or prevention of diseases related to activity of CRTH2.
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