发明公开
EP2788334A1 LABELED ALGINATE CONJUGATES FOR MOLECULAR IMAGING APPLICATIONS
有权
标识为分子成像应用ALGINATKONJUGATE
- 专利标题： LABELED ALGINATE CONJUGATES FOR MOLECULAR IMAGING APPLICATIONS
- 专利标题（中）： 标识为分子成像应用ALGINATKONJUGATE
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申请号： EP12808605.5申请日： 2012-12-07
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公开(公告)号： EP2788334A1公开(公告)日： 2014-10-15
- 发明人: RUAN, Fuqiang , DECKWERTH, Thomas L. , MEGLASSON, Martin D.
- 申请人： Bellerophon BCM LLC
- 申请人地址： 53 Frontage Road, Third Floor P.O. Box 9001 Hampton, NJ 08827 US
- 专利权人： Bellerophon BCM LLC
- 当前专利权人： Bellerophon BCM LLC
- 当前专利权人地址： 53 Frontage Road, Third Floor P.O. Box 9001 Hampton, NJ 08827 US
- 代理机构： Vossius & Partner
- 优先权： US201161568796P 20111209
- 国际公布： WO2013086396 20130613
- 主分类号： C07D255/02
- IPC分类号： C07D255/02
摘要：
Described are bifunctional NOTA-based derivatives capable of conjugating with alginate and with metal ions, as well as NOTA-alginate conjugates which can be labeled with stable or radioactive metal ions. Also described are conjugation methods of the bifunctional NOTA-based linker with alginate, and methods of using radiometal-labeled NOTA-alginate conjugates or other radio-labeled alginate conjugates as imaging reagents.
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