发明授权
- 专利标题: USE OF INHIBITORS OF THE ACTIVITY OR FUNCTION OF PI3K
- 专利标题(中): 使用PI3K的活性或功能的抑制剂
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申请号: EP12818825.7申请日: 2012-12-14
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公开(公告)号: EP2790705B1公开(公告)日: 2017-12-06
- 发明人: COOKE, Nigel Graham , FERNANDES GOMES DOS SANTOS, Paulo Antonio , FURET, Pascal , HEBACH, Christina , HÖGENAUER, Klemens , HOLLINGWORTH, Gregory , KALIS, Christoph , LEWIS, Ian , SMITH, Alexander Baxter , SOLDERMANN, Nicolas , STAUFFER, Frédéric , STRANG, Ross , STOWASSER, Frank , TUFILLI, Nicola , VON MATT, Anette , WOLF, Romain , ZECRI, Frédéric
- 申请人: Novartis AG
- 申请人地址: Lichtstrasse 35 4056 Basel CH
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: Lichtstrasse 35 4056 Basel CH
- 代理机构: Marti, Christiane
- 优先权: US201161576194P 20111215
- 国际公布: WO2013088404 20130620
- 主分类号: A61K31/517
- IPC分类号: A61K31/517 ; A61K31/519 ; A61P33/00
摘要:
The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.
公开/授权文献
- EP2790705A1 USE OF INHIBITORS OF THE ACTIVITY OR FUNCTION OF PI3K 公开/授权日:2014-10-22
信息查询
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