发明公开
- 专利标题： SUBSTITUTED BENZOTHIENYL - PYRROLOTRIAZINES AND USES THEREOF IN THE TREATMENT CANCER
- 专利标题（中）： 取代噻吩基吡咯并和它们在癌症治疗
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申请号： EP12809680.7申请日： 2012-12-11
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公开(公告)号： EP2791143A1公开(公告)日： 2014-10-22
- 发明人: COLLIN, Marie-Pierre , BROHM, Dirk , HÉROULT, Mélanie , LOBELL, Mario , HÜBSCH, Walter , LUSTIG, Klemens , GRÜNEWALD, Sylvia , BÖMER, Ulf , VÖHRINGER, Verena , LINDNER, Niels
- 申请人： Bayer Intellectual Property GmbH , Bayer Pharma Aktiengesellschaft
- 申请人地址： Alfred-Nobel-Str. 10 40789 Monheim am Rhein DE
- 专利权人： Bayer Intellectual Property GmbH,Bayer Pharma Aktiengesellschaft
- 当前专利权人： Bayer Intellectual Property GmbH,Bayer Pharma Aktiengesellschaft
- 当前专利权人地址： Alfred-Nobel-Str. 10 40789 Monheim am Rhein DE
- 代理机构： BIP Patents
- 优先权： EP11193839 20111215
- 国际公布： WO2013087647 20130620
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/53 ; A61P35/00
摘要：
This invention relates to novel substituted 5-(l-benzothiophen-2-yl)pyrrolo[2,l-fJ[l,2,4]triazin-4-amine derivatives having protein tyrosine kinase inhibitory activities, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating proliferative disorders, in particular cancer and tumor diseases.
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