发明公开
EP2791336A2 METHODS, SYSTEMS, AND COMPOSITIONS FOR CELL-DERIVED/VESICLE-BASED MICRORNA DELIVERY
有权
方法，细胞/囊泡交付获得微RNA体系和组合物
- 专利标题： METHODS, SYSTEMS, AND COMPOSITIONS FOR CELL-DERIVED/VESICLE-BASED MICRORNA DELIVERY
- 专利标题（中）： 方法，细胞/囊泡交付获得微RNA体系和组合物
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申请号： EP12809048.7申请日： 2012-12-13
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公开(公告)号： EP2791336A2公开(公告)日： 2014-10-22
- 发明人: KATAKOWSKI, Mark, E. , BULLER, Benjamin, A.L. , CHOPP, Michael
- 申请人： Henry Ford Health System
- 申请人地址： 1 Ford Place Detroit, MI 48202 US
- 专利权人： Henry Ford Health System
- 当前专利权人： Henry Ford Health System
- 当前专利权人地址： 1 Ford Place Detroit, MI 48202 US
- 代理机构： Nash, David Allan
- 优先权： US201161570081P 20111213
- 国际公布： WO2013090523 20130620
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C12N15/11 ; A61K48/00 ; A61K31/713
摘要：
Some embodiments comprise methods, systems, and compositions to produce and/or administer modified exosomes or other vesicles containing one or more selected microRNAs, including but not limited to, miR-146b. Some embodiments also comprise the therapeutic administration and use of such modified exosomes and/or producer cells to treat mammalian injuries and diseases, including in human beings.
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