发明公开
- 专利标题: MEASUREMENT OF AUTOANTIBODIES AT LOW CONDUCTIVITY CONDITIONS WITH INCREASED SENSITIVITY
- 专利标题(中): 自身抗体测量低电导率使用更高的灵敏度
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申请号: EP12820994.7申请日: 2012-12-13
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公开(公告)号: EP2791675A1公开(公告)日: 2014-10-22
- 发明人: WEBER, Alfred , ENGELMAIER, Andrea , SCHWARZ, Hans-Peter
- 申请人: Baxter International Inc , Baxter Healthcare SA
- 申请人地址: One Baxter Parkway Deerfield, IL 60015 US
- 专利权人: Baxter International Inc,Baxter Healthcare SA
- 当前专利权人: Baxter International Inc,Baxter Healthcare SA
- 当前专利权人地址: One Baxter Parkway Deerfield, IL 60015 US
- 代理机构: HOFFMANN EITLE
- 优先权: US201161570211P 20111213
- 国际公布: WO2013090636 20130620
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; G01N33/564 ; A61K39/395 ; G01N33/543
摘要:
Methods for detecting or capturing low-avidity autoantibodies in a biological sample are provided. Target antigen used to assay for the low-avidity autoantibodies of interest is immobilized on a solid phase. The biological sample is contacted under low conductivity condition with the target antigen for which the autoantibodies has specific binding affinity. Binding of the target antigen to the autoantibodies of interest in the biological sample is then detected to ascertain the presence or concentration of the autoantibodies of interest.
公开/授权文献
- EP2791675B1 MEASUREMENT OF AUTOANTIBODIES IN LOW CONDUCTIVITY CONDITIONS 公开/授权日:2018-04-25
信息查询
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