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EP2791675A1 MEASUREMENT OF AUTOANTIBODIES AT LOW CONDUCTIVITY CONDITIONS WITH INCREASED SENSITIVITY 有权
自身抗体测量低电导率使用更高的灵敏度

MEASUREMENT OF AUTOANTIBODIES AT LOW CONDUCTIVITY CONDITIONS WITH INCREASED SENSITIVITY
摘要:
Methods for detecting or capturing low-avidity autoantibodies in a biological sample are provided. Target antigen used to assay for the low-avidity autoantibodies of interest is immobilized on a solid phase. The biological sample is contacted under low conductivity condition with the target antigen for which the autoantibodies has specific binding affinity. Binding of the target antigen to the autoantibodies of interest in the biological sample is then detected to ascertain the presence or concentration of the autoantibodies of interest.
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