发明公开
- 专利标题： METHODS AND MATERIALS FOR ASSESSING LOSS OF HETEROZYGOSITY
- 专利标题（中）： 方法和材料杂客观评定的损失
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申请号： EP12860530.0申请日： 2012-12-21
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公开(公告)号： EP2794907A1公开(公告)日： 2014-10-29
- 发明人: ABKEVICH, Victor , GUTIN, Alexander , TIMMS, Kirsten , LANCHBURY, Jerry
- 申请人： Myriad Genetics, Inc. , Abkevich, Victor , Gutin, Alexander , Timms, Kirsten , Lanchbury, Jerry
- 申请人地址： 320 Wakara Way Salt Lake City, UT 84108 US
- 专利权人： Myriad Genetics, Inc.,Abkevich, Victor,Gutin, Alexander,Timms, Kirsten,Lanchbury, Jerry
- 当前专利权人： Myriad Genetics, Inc.,Abkevich, Victor,Gutin, Alexander,Timms, Kirsten,Lanchbury, Jerry
- 当前专利权人地址： 320 Wakara Way Salt Lake City, UT 84108 US
- 代理机构： Vossius & Partner
- 优先权： US201161578713P 20111221; US201261654402P 20120601
- 国际公布： WO2013096843 20130627
- 主分类号： C12Q1/04
- IPC分类号： C12Q1/04 ; C12Q1/68 ; C12N15/11
摘要：
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.
公开/授权文献
- EP2794907B2 METHODS AND MATERIALS FOR ASSESSING LOSS OF HETEROZYGOSITY 公开/授权日：2022-11-23
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