发明公开
EP2796442A1 CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE
审中-公开
ANALOG COMPOSITE从CAJANINSTRUKTUR，工艺及其制造和使用
- 专利标题： CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE
- 专利标题（中）： ANALOG COMPOSITE从CAJANINSTRUKTUR，工艺及其制造和使用
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申请号： EP12859858.8申请日： 2012-12-18
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公开(公告)号： EP2796442A1公开(公告)日： 2014-10-29
- 发明人: LI, Zhuorong , JI, Xingyue , XUE, Situ , ZHENG, Guanghui , LI, Yuhuan , TAO, Peizhen , JIANG, Jiandong
- 申请人： Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
- 申请人地址： No.1 Tiantan Xili Dongcheng District Beijing 100050 CN
- 专利权人： Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
- 当前专利权人： Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
- 当前专利权人地址： No.1 Tiantan Xili Dongcheng District Beijing 100050 CN
- 代理机构： Michalski Hüttermann & Partner Patentanwälte mbB
- 优先权： CN201110439374 20111223
- 国际公布： WO2013091282 20130627
- 主分类号： C07C65/03
- IPC分类号： C07C65/03 ; C07C65/05 ; C07C65/28 ; C07C69/78 ; C07C69/88 ; C07C69/92 ; C07C51/09 ; C07C67/14 ; C07C67/16 ; A61K31/192 ; A61P3/06 ; A61P3/10 ; A61P3/14 ; A61P25/28 ; A61P25/00 ; A61P31/04 ; A61P31/12
摘要：
Provided are cajanine structure analogous compounds, synthesis method and pharmacological effects thereof, the compounds of the present invention having the structure as represented by general formulas I, II, III, IV and V. Also provided are pharmaceutical compositions containing the compounds as active ingredient, and uses thereof; the compounds of the present invention having the pharmacological activities such as anti-virus, anti-virus-infection, nerve protection, anti-metabolic-diseases and the like. Also provided is a chemical total synthesis preparation method of the natural products cajanine, cajanine A and cajanine C. The present invention lays a foundation for the in-depth study and development of the compounds as clinical drugs in the future.
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