发明公开
EP2797875A1 CINNAMIC ACID HYDROXYAMIDES AS INHIBITORS OF HISTONE DEACETYLASE 8
审中-公开
ZIMTSÄUREHYDROXYAMIDEAS蛋白去乙酰化酶8的抑制剂
- 专利标题： CINNAMIC ACID HYDROXYAMIDES AS INHIBITORS OF HISTONE DEACETYLASE 8
- 专利标题（中）： ZIMTSÄUREHYDROXYAMIDEAS蛋白去乙酰化酶8的抑制剂
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申请号： EP12863933.3申请日： 2012-12-19
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公开(公告)号： EP2797875A1公开(公告)日： 2014-11-05
- 发明人: VERNER, Erik , CHEN, Wei , BALASUBRAMANIAN, Sriram
- 申请人： Pharmacyclics, Inc.
- 申请人地址： 995 East Arques Avenue Sunnyvale, CA 94085 US
- 专利权人： Pharmacyclics, Inc.
- 当前专利权人： Pharmacyclics, Inc.
- 当前专利权人地址： 995 East Arques Avenue Sunnyvale, CA 94085 US
- 代理机构： HGF Limited
- 优先权： US201161581459P 20111229
- 国际公布： WO2013101600 20130704
- 主分类号： C07C235/34
- IPC分类号： C07C235/34 ; A61K31/16 ; A61P43/00
摘要：
Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activy of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of HDAC8 activity.
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