发明公开
- 专利标题： AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS
- 专利标题（中）： 氨基嘧啶衍生物ALS LRRK2-MODULATOREN
-
申请号： EP12797826.0申请日： 2012-11-28
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公开(公告)号： EP2807152A1公开(公告)日： 2014-12-03
- 发明人: BAKER-GLENN, Charles , CHAMBERS, Mark , CHAN, Bryan K. , CHEN, Huifen , ESTRADA, Anthony , SHORE, David , SWEENEY, Zachary
- 申请人： F.Hoffmann-La Roche AG
- 申请人地址： Grenzacherstrasse 124 4070 Basel CH
- 专利权人： F.Hoffmann-La Roche AG
- 当前专利权人： F.Hoffmann-La Roche AG
- 当前专利权人地址： Grenzacherstrasse 124 4070 Basel CH
- 代理机构： Müller-Afraz, Simona
- 优先权： US201161564753P 20111129
- 国际公布： WO2013079493 20130606
- 主分类号： C07D239/42
- IPC分类号： C07D239/42 ; C07D239/48 ; A61K31/505
摘要：
Compounds of the formula (I), or pharmaceutically acceptable salts thereof, wherein m, n. X, R
1 , R
2 , R
3 , R
4 and R
5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease.
1 , R
2 , R
3 , R
4 and R
5 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease.
公开/授权文献
- EP2807152B1 AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS 公开/授权日：2017-07-19
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