发明公开
- 专利标题: ADENOVIRAL VECTOR-BASED MALARIA VACCINE
- 专利标题(中): ON疟疾疫苗BASED腺病毒载体
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申请号: EP13703506.9申请日: 2013-02-01
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公开(公告)号: EP2809346A1公开(公告)日: 2014-12-10
- 发明人: BRUDER, Joseph T. , GALL, Jason G., D. , MCVEY, Duncan , BROUGH, Douglas E.
- 申请人: GenVec, Inc.
- 申请人地址: 910 Clopper Road, Suite 220N Gaithersburg, MD 20878 US
- 专利权人: GenVec, Inc.
- 当前专利权人: GenVec, Inc.
- 当前专利权人地址: 910 Clopper Road, Suite 220N Gaithersburg, MD 20878 US
- 代理机构: Hoeger, Stellrecht & Partner Patentanwälte
- 优先权: US201261593953P 20120202; US201261593964P 20120202; US201261593980P 20120202
- 国际公布: WO2013116591 20130808
- 主分类号: A61K39/015
- IPC分类号: A61K39/015 ; C12N7/00 ; C12N15/861
摘要:
The invention provides an adenovirus or adenoviral vector characterized by comprising a nucleic acid sequence encoding one or more Plasmodium antigens and one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein, as well as a method of inducing an immune response against Plasmodium falciparum in a mammal by administering the adenovirus or adenoviral vector to the mammal.
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