发明公开
- 专利标题： BOUVARDIN DERIVATIVES AND THERAPEUTIC USES THEREOF
- 专利标题（中）： BOUVARDIN衍生物及其治疗用途
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申请号： EP13751205.9申请日： 2013-02-21
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公开(公告)号： EP2817004A1公开(公告)日： 2014-12-31
- 发明人: SU, Tin, Tin , GLACSTONE, Mara, N. , ZHANG, Gan , SAMMAKIA, Tarek
- 申请人： The Regents of The University of Colorado, A Body Corporate , Suvica, Inc.
- 申请人地址： 1800 Grant Street, 8th Floor Denver, CO 80203 US
- 专利权人： The Regents of The University of Colorado, A Body Corporate,Suvica, Inc.
- 当前专利权人： The Regents of The University of Colorado, A Body Corporate,Suvica, Inc.
- 当前专利权人地址： 1800 Grant Street, 8th Floor Denver, CO 80203 US
- 代理机构： Russell, Tim
- 优先权： US201261601981P 20120222; US201261702706P 20120918
- 国际公布： WO2013126617 20130829
- 主分类号： A61K31/165
- IPC分类号： A61K31/165
摘要：
The present invention is directed at bouvardin analogs arid related compounds for the treatment of disorders including cancer. Provided herein are bouvardin analogs and related compounds, pharmaceutical compositions and kits comprising at least one bouvardin analog or related compound, and methods for treating disorders including cancer. In some aspects the compounds inhibit translation elongation at the ribosome. The compounds are used in combination with radiation therapy or with known chemotherapeutic compositions.
公开/授权文献
- EP2817004B1 BOUVARDIN DERIVATIVES AND THERAPEUTIC USES THEREOF 公开/授权日：2018-04-11
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