发明公开
EP2822954A1 POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
有权
多环CARBAMOYLPYRIDONVERBINDUNGEN和它们的药物用途
- 专利标题： POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE
- 专利标题（中）： 多环CARBAMOYLPYRIDONVERBINDUNGEN和它们的药物用途
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申请号： EP13815937.1申请日： 2013-12-19
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公开(公告)号： EP2822954A1公开(公告)日： 2015-01-14
- 发明人: JIN, Haolun , LAZERWITH, Scott, E. , MARTIN, Teresa, Alejandra, Trejo , BACON, Elizabeth, M. , COTTELL, Jeromy, J. , CAI, Zhenhong, R. , PYUN, Hyung-Jung , MORGANELLI, Philip, Anthony , JI, Mingzhe , TAYLOR, James, G. , CHEN, Xiaowu , MISH, Michael, R. , DESAI, Manoj, C.
- 申请人： Gilead Sciences, Inc.
- 申请人地址： 333 Lakeside Drive Foster City, CA 94404 US
- 专利权人： Gilead Sciences, Inc.
- 当前专利权人： Gilead Sciences, Inc.
- 当前专利权人地址： 333 Lakeside Drive Foster City, CA 94404 US
- 代理机构： Carpmaels & Ransford LLP
- 优先权： US201261745375P 20121221; US201361788397P 20130315; US201361845803P 20130712
- 国际公布： WO2014100323 20140626
- 主分类号： C07D498/14
- IPC分类号： C07D498/14 ; C07D471/04 ; C07D471/14 ; C07D471/22 ; C07D487/04
摘要：
Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R 1 , X, W, Y 1 , Y 2 , Z 1 and Z 4 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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