发明公开
- 专利标题： NOVEL TRIAZINE DERIVATIVE
- 专利标题（中）： 新的三嗪衍生物
-
申请号： EP13758233.4申请日： 2013-03-07
-
公开(公告)号： EP2824099A1公开(公告)日： 2015-01-14
- 发明人: KAWAHATA, Wataru , ASAMI, Tokiko , SAWA, Masaaki , ASAMITSU, Yuko , IRIE, Takayuki , MIYAKE, Takahiro , KIYOI, Takao
- 申请人： Carna Biosciences, Inc.
- 申请人地址： 1-5-5, Minatojima-Minamimachi Chuo-ku Kobe-shi, Hyogo 650-0047 JP
- 专利权人： Carna Biosciences, Inc.
- 当前专利权人： Carna Biosciences, Inc.
- 当前专利权人地址： 1-5-5, Minatojima-Minamimachi Chuo-ku Kobe-shi, Hyogo 650-0047 JP
- 代理机构： Sajda, Wolf E.
- 优先权： JP2012053543 20120309; JP2012100646 20120426; JP2012147111 20120629; JP2012280811 20121225
- 国际公布： WO2013133367 20130912
- 主分类号： C07D251/42
- IPC分类号： C07D251/42 ; A61K31/53 ; A61K31/5377 ; A61P19/00 ; A61P29/00 ; A61P35/00 ; A61P35/02 ; A61P37/06 ; A61P43/00
摘要：
To provide a novel triazine derivative represented by the following formula (I):
A triazine derivative represented by the following formula (I) :
wherein
R 1 represents a substituted or unsubstituted aryl group, a substituted or unsubstituted heterocyclic ring, a substituted or unsubstituted heterocyclic fused ring, or a substituted or unsubstituted alkynyl group,
R 2 represents a hydrogen atom, a halogen atom, a substituted or unsubstituted lower alkyl group, or a substituted or unsubstituted alkoxy group,
R 3 represents a substituted or unsubstituted aryl group, a substituted or unsubstituted heterocyclic ring, or a substituted or unsubstituted heterocyclic fused ring,
R 4 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted amino group, or a halogen atom, and
R 5 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, or R 1 and R 5 may be combined to form a saturated or unsaturated 5- to 6-membered ring, thereby forming a multiply fused ring,
or a pharmaceutically acceptable salt thereof.
A triazine derivative represented by the following formula (I) :
wherein
R 1 represents a substituted or unsubstituted aryl group, a substituted or unsubstituted heterocyclic ring, a substituted or unsubstituted heterocyclic fused ring, or a substituted or unsubstituted alkynyl group,
R 2 represents a hydrogen atom, a halogen atom, a substituted or unsubstituted lower alkyl group, or a substituted or unsubstituted alkoxy group,
R 3 represents a substituted or unsubstituted aryl group, a substituted or unsubstituted heterocyclic ring, or a substituted or unsubstituted heterocyclic fused ring,
R 4 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted amino group, or a halogen atom, and
R 5 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, or R 1 and R 5 may be combined to form a saturated or unsaturated 5- to 6-membered ring, thereby forming a multiply fused ring,
or a pharmaceutically acceptable salt thereof.
信息查询
