发明公开
EP2825160A1 A SIK INHIBITOR FOR USE IN A METHOD OF TREATING AN INFLAMMATORY AND/OR IMMUNE DISORDER
审中-公开
SIK抑制剂FOR USE IN一种用于治疗炎性和/或免疫疾病
- 专利标题： A SIK INHIBITOR FOR USE IN A METHOD OF TREATING AN INFLAMMATORY AND/OR IMMUNE DISORDER
- 专利标题（中）： SIK抑制剂FOR USE IN一种用于治疗炎性和/或免疫疾病
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申请号： EP13711103.5申请日： 2013-03-13
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公开(公告)号： EP2825160A1公开(公告)日： 2015-01-21
- 发明人: COHEN, Philip , CLARK, Kristopher , CHOI, Hwan, Geun , GRAY, Nathanael
- 申请人： University Court of The University of Dundee , DANA-FARBER CANCER INSTITUTE, INC.
- 申请人地址： Nethergate Perth Road Dundee DD1 4HN GB
- 专利权人： University Court of The University of Dundee,DANA-FARBER CANCER INSTITUTE, INC.
- 当前专利权人： University Court of The University of Dundee,DANA-FARBER CANCER INSTITUTE, INC.
- 当前专利权人地址： Nethergate Perth Road Dundee DD1 4HN GB
- 代理机构： Chapman, Paul Gilmour
- 优先权： GB201204384 20120313
- 国际公布： WO2013136070 20130919
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; A61K31/506 ; A61K31/519 ; A61K31/5377 ; A61P29/00
摘要：
The present invention relates to the discovery that salt inducible kinases (SIKs) suppress the formation of anti-inflammatory molecules such as IL-10, which are important for the resolution of inflammation and identifies SIK inhibitors that may be used to treat disorders associated with undesirable inflammation, such as inflammatory bowel disease and/or autoimmune disorders.
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