发明公开
- 专利标题: TRANILAST COMPOSITIONS AND COCRYSTALS
- 专利标题(中): 碎末组合物和共晶体
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申请号: EP13722102.4申请日: 2013-03-29
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公开(公告)号: EP2830590A1公开(公告)日: 2015-02-04
- 发明人: HOLLAND, Joanne , FRAMPTON, Christopher
- 申请人: Nuformix Limited , Holland, Joanne , Frampton, Christopher
- 申请人地址: Edinburgh House St. Johns Innovation Park Cowley Road Cambridge, Cambridgeshire CB4 0DS GB
- 专利权人: Nuformix Limited,Holland, Joanne,Frampton, Christopher
- 当前专利权人: Nuformix Limited,Holland, Joanne,Frampton, Christopher
- 当前专利权人地址: Edinburgh House St. Johns Innovation Park Cowley Road Cambridge, Cambridgeshire CB4 0DS GB
- 代理机构: Jacobi, Markus Alexander
- 优先权: US201261618639P 20120330
- 国际公布: WO2013144916 20131003
- 主分类号: A61K9/08
- IPC分类号: A61K9/08 ; A61K9/14 ; A61K31/196 ; C07C235/38 ; A61P27/14 ; A61P35/00
摘要:
Mew tranilast complexes and new tranilast cocrystais are disclosed. These include all tranilast nicotinamide complex, a 1:1 tranilast nicotinamide cocrystal, a 1:1 tranilast saccharin complex, a 1:1 tranilast saccharin cocrystal, a 1:1 tranilast gentisic acid complex, a 1:1 tranilast gentisic acid cocrystal, a 1:1 tranilast salicylic acid complex, a 1:1 tranilast salicylic acid cocrystal, a 1:1 tranilast urea complex, a 1:1 tranilast urea cocrystal, a 1:1 tranilast 4-amtnoben2oic acid complex, a 1:1 tranilast 4-am!nobers2oic acid cocrystal, a 1:1 tranilast 2,4-di′hydroxybenzoic acid complex and a 1:1 tranilast 2,4-dihydroxybenzoic acid cocrystal. Also disclosed are pharmaceutical compositions containing a tranilast complex or cocrystal of the invention and a pharmaceutically acceptable carrier. Methods of treatment using the tranilast complexes and cocrystais as well as the pharmaceutical compositions are disclosed.
公开/授权文献
- EP2830590B1 TRANILAST COMPOSITIONS AND COCRYSTALS 公开/授权日:2017-06-28
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