发明公开
- 专利标题: NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF
- 专利标题(中): 含氮杂环化合物或其盐
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申请号: EP13778349.4申请日: 2013-04-16
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公开(公告)号: EP2840080A1公开(公告)日: 2015-02-25
- 发明人: TAKASAKI, Masaru , TSUJINO, Toshiaki , TANABE, Shintarou , OOKUBO, Megumi , SATO, Kimihiko , HIRAI, Atsushi , TERADA, Daisuke , INUKI, Shinsuke , MIZUMOTO, Shinsuke
- 申请人: Fujifilm Corporation
- 申请人地址: 26-30 Nishiazabu 2-chome Minato-ku Tokyo 106-8620 JP
- 专利权人: Fujifilm Corporation
- 当前专利权人: Fujifilm Corporation
- 当前专利权人地址: 26-30 Nishiazabu 2-chome Minato-ku Tokyo 106-8620 JP
- 代理机构: Hoffmann Eitle
- 优先权: JP2012094184 20120417; JP2013082479 20130315
- 国际公布: WO2013157540 20131024
- 主分类号: C07D213/74
- IPC分类号: C07D213/74 ; A61K31/505 ; A61K31/506 ; A61K31/5377 ; A61K31/55 ; A61K31/551 ; A61P35/02 ; A61P43/00 ; C07D239/48 ; C07D239/49 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/12 ; C07D409/12
摘要:
The object is to provide an Fms-like tyrosine kinase 3 (FLT3) inhibitor useful as a therapeutic agent for acute myeloid leukemia (AML). A novel nitrogen-containing heterocyclic compound represented by the general formula [1] or a salt thereof is provided. The compound or a salt thereof of the present invention can be used as an active ingredient of a pharmaceutical composition for a treatment of a disease or condition relating to FLT3, such as acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL).
公开/授权文献
- EP2840080B1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF 公开/授权日:2017-12-06
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