发明公开
EP2855428A1 N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN
审中-公开
N-SUBSTITUIERTE BENZAMIDE UND IHRE VERWENDUNG IN DER SCHMERZBEHANDLUNG
- 专利标题： N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN
- 专利标题（中）： N-SUBSTITUIERTE BENZAMIDE UND IHRE VERWENDUNG IN DER SCHMERZBEHANDLUNG
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申请号： EP13726976.7申请日： 2013-05-21
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公开(公告)号： EP2855428A1公开(公告)日： 2015-04-08
- 发明人: ANDREZ, Jean-Christophe , CHOWDHURY, Sultan , DECKER, Shannon , DEHNHARDT, Christoph, Martin , FOCKEN, Thilo , GRIMWOOD, Michael, Edward , HEMEON, Ivan, William , JIA, Qi , LI, Jun , ORTWINE, Daniel, F. , SAFINA, Brian , SHENG, Tao , SUN, Shaoyi , SUTHERLIN, Daniel, P. , WILSON, Michael, Scott , ZENOVA, Alla, Yurevna
- 申请人： Genentech, Inc. , Xenon Pharmaceuticals Inc.
- 申请人地址： One DNA Way South San Francisco, CA 94080-4990 US
- 专利权人： Genentech, Inc.,Xenon Pharmaceuticals Inc.
- 当前专利权人： Genentech, Inc.,Xenon Pharmaceuticals Inc.
- 当前专利权人地址： One DNA Way South San Francisco, CA 94080-4990 US
- 代理机构： Bailey, Sam Rogerson
- 优先权： PCT/IB2012/001324 20120522; US201261650934P 20120523; US201361785601P 20130314
- 国际公布： WO2013177224 20131128
- 主分类号： C07C311/51
- IPC分类号： C07C311/51 ; C07D207/08 ; C07D213/82 ; C07D307/12 ; A61K31/44 ; A61K31/445 ; A61K31/18 ; A61P25/04
摘要：
The invention provides novel compounds having the general formula: and pharmaceutically acceptable salts thereof, wherein the variables RA, subscript n, ring A, X2, L, subscript m, X1, B, R1, R2, R3, R4, R5 and RN have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.
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