发明公开
- 专利标题： IMIDAZOPYRAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY
- 专利标题（中）： 咪唑嗪衍生物调节剂TNF-AKTIVITÄT
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申请号： EP13734128.5申请日： 2013-07-05
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公开(公告)号： EP2872511A1公开(公告)日： 2015-05-20
- 发明人: BENTLEY, Jonathan Mark , BROOKINGS, Daniel Christopher , BROWN, Julien Alistair , CAIN, Thomas Paul , GLEAVE, Laura Jane , HEIFETZ, Alexander , JACKSON, Victoria Elizabeth , JOHNSTONE, Craig , LEIGH, Deborah , MADDEN, James , PORTER, John Robert , SELBY, Matthew Duncan , ZHU, Zhaoning
- 申请人： UCB Biopharma SPRL
- 申请人地址： 60, Allée de la Recherche 1070 Brussels BE
- 专利权人： UCB Biopharma SPRL
- 当前专利权人： UCB Biopharma SPRL
- 当前专利权人地址： 60, Allée de la Recherche 1070 Brussels BE
- 代理机构： Duckworth, Timothy John
- 优先权： GB201212513 20120713
- 国际公布： WO2014009296 20140116
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/425 ; A61P29/00
摘要：
A series of imidazo[1,2-α]pyrazine derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorder; and oncological disorders.
公开/授权文献
- EP2872511B1 IMIDAZOPYRAZINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY 公开/授权日：2019-01-16
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