发明公开
- 专利标题: MINERALOCORTICOID RECEPTOR ANTAGONISTS
- 专利标题(中): 盐皮质激素受体拮抗剂
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申请号: EP13819260申请日: 2013-07-15
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公开(公告)号: EP2874621A4公开(公告)日: 2016-04-27
- 发明人: CERNAK THIMOTHY A , DYKSTRA KEVIN D , SHEN DONG-MING , LIU KUN , STAMFORD ANDREW , TAN JOHN QIANG
- 申请人: MERCK SHARP & DOHME
- 专利权人: MERCK SHARP & DOHME
- 当前专利权人: MERCK SHARP & DOHME
- 优先权: US201261673615 2012-07-19; US201261673592 2012-07-19
- 主分类号: A61K31/416
- IPC分类号: A61K31/416 ; C07D231/56
摘要:
The present invention is directed to compounds of the Formula I: as well as pharmaceutically acceptable salts thereof, that may be useful for treating aldosterone-mediated diseases. The invention furthermore relates to specific diastereomers and enantiomers of the compounds, to processes for preparing compounds of the Formula I, to their potential use for the therapy and prophylaxis of the above-mentioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical compositions which comprise compounds of the Formula I.
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