发明公开
- 专利标题： HIV TREATMENT WITH AMIDO-SUBSTITUTED PYRIMIDINONE DERIVATIVES
- 专利标题（中）： 用酰胺取代的嘧啶酮衍生物治疗HIV
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申请号： EP13819609.2申请日： 2013-07-16
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公开(公告)号： EP2875024A1公开(公告)日： 2015-05-27
- 发明人: COLEMAN, Paul, J. , WALJI, Abbas , DANG, Qun , BENNETT, David, J. , CLAS, Sophie, D. , WAI, John , BALSELLS-PADROS, Jaume , WU, Henry, Y. , SMITH, Ronald, L. , NOFSINGER, Rebecca , SANCHEZ, Rosa, I.
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构： Jaap, David Robert
- 优先权： US201261673886P 20120720
- 国际公布： WO2014014933 20140123
- 主分类号： C07D413/12
- IPC分类号： C07D413/12 ; A61P31/18 ; A61K31/506
摘要：
The present invention relates to Amido-Substituted Pyrimidinone Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein R
1 , R
2 , R
3 , R
4 , R
5 and R
6 are as defined herein. The present invention also relates to compositions comprising at least one Amido-Substituted Pyrimidinone Derivative, and methods of using the Amido-Substituted Pyrimidinone Derivatives for treating or preventing HIV infection in a subject.
1 , R
2 , R
3 , R
4 , R
5 and R
6 are as defined herein. The present invention also relates to compositions comprising at least one Amido-Substituted Pyrimidinone Derivative, and methods of using the Amido-Substituted Pyrimidinone Derivatives for treating or preventing HIV infection in a subject.
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