发明授权
- 专利标题: ASGPR ANTIBODIES AND USES THEREOF
- 专利标题(中): ASGPR抗体及其用途
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申请号: EP13745419.5申请日: 2013-08-06
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公开(公告)号: EP2882775B1公开(公告)日: 2018-02-14
- 发明人: HOFER, Thomas , JI, Changhua , MOESSNER, Ekkehard , UMANA, Pablo
- 申请人: Roche Glycart AG
- 申请人地址: Wagistrasse 18 8952 Schlieren CH
- 专利权人: Roche Glycart AG
- 当前专利权人: Roche Glycart AG
- 当前专利权人地址: Wagistrasse 18 8952 Schlieren CH
- 代理机构: Cueni, Leah Noëmi
- 优先权: US201261681239P 20120809
- 国际公布: WO2014023709 20140213
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K38/19 ; A61P31/14 ; A61P35/00
摘要:
The present invention generally relates to antibodies specific for asialoglycoprotein receptor (ASGPR) and their use for selectively delivering effector moieties that influence cellular activity. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies of the invention, and to methods of using them in the treatment of disease.
公开/授权文献
- EP2882775A1 ASGPR ANTIBODIES AND USES THEREOF 公开/授权日:2015-06-17
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