发明授权
- 专利标题： BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS
- 专利标题（中）： 双环氮杂化合物作为蕈毒碱M1受体的激动剂
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申请号： EP13766641.8申请日： 2013-09-18
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公开(公告)号： EP2897948B1公开(公告)日： 2016-08-31
- 发明人: BROWN, Giles Albert , CANSFIELD, Julie Elaine , CONGREVE, Miles Stuart , PICKWORTH, Mark , TEHAN, Benjamin Gerald
- 申请人： Heptares Therapeutics Limited
- 申请人地址： BioPark Broadwater Road Welwyn Garden City Hertfordshire AL7 3AX GB
- 专利权人： Heptares Therapeutics Limited
- 当前专利权人： Heptares Therapeutics Limited
- 当前专利权人地址： BioPark Broadwater Road Welwyn Garden City Hertfordshire AL7 3AX GB
- 代理机构： Stratagem IPM Limited
- 优先权： US201261702330P 20120918; US201361823606P 20130515
- 国际公布： WO2014045031 20140327
- 主分类号： C07D401/08
- IPC分类号： C07D401/08 ; C07D451/04 ; C07B59/00 ; A61K31/439 ; A61P25/28
摘要：
This invention relates to compounds (Formula (1)) that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where R1-R5, X1, X2 and p are as defined herein.
公开/授权文献
- EP2897948A1 BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS 公开/授权日：2015-07-29
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