发明公开
- 专利标题: T CELL MODIFYING COMPOUNDS AND USES THEREOF
- 专利标题(中): T-CELL-改性化合物及其用途
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申请号: EP13845951申请日: 2013-10-10
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公开(公告)号: EP2906684A4公开(公告)日: 2016-04-27
- 发明人: GREGORY PHILIP D , HOLMES MICHAEL C
- 申请人: SANGAMO BIOSCIENCES INC
- 专利权人: SANGAMO BIOSCIENCES INC
- 当前专利权人: SANGAMO BIOSCIENCES INC
- 优先权: US201261712028 2012-10-10
- 主分类号: C12N5/071
- IPC分类号: C12N5/071 ; C12N15/00 ; C12N15/87
摘要:
Methods and compositions for modifying T-cells in which PD1 and/or CTLA-4 is repressed and/or inactivated using fusion proteins such as artificial transcription factors and nucleases.
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