An apparatus adapted to automatically handle larvae grafting operations in beekeeping is described, which comprises: - means for containing at least one bee brood comb (3), said comb comprising cells suitable for receiving bee larvae; - means for containing at least one support (4) for artificial cells suitable for receiving bee larvae; - a movable system (5) comprising: an image sensor (8); a manipulator (7) adapted to pick said bee larvae from the cells of said at least one comb (3) and to place them into said artificial cells; handling means (6) adapted to move said image sensor (8) and manipulator (7) in the apparatus; - control means adapted to control the movement "of said~haridiing means "(6), so that said' image sensor (8) will identify the positions of those larvae which are suited to being picked from the cells of said at least one comb (3), and said manipulator (7) will act in accordance with said identified larvae.