发明授权
- 专利标题： BENZOMORPHAN ANALOGS AND THE USE THEREOF
- 专利标题（中）： BENZOMORPHAN类似物及其用途
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申请号： EP13818371.0申请日： 2013-11-08
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公开(公告)号： EP2917182B1公开(公告)日： 2018-01-03
- 发明人: LOCKMAN, Jeffrey , TAFESSE, Laykea , YAO, Jiangchao , YU, Jianming
- 申请人： Purdue Pharma LP
- 申请人地址： One Stamford Forum 201 Tresser Boulevard Stamford, CT 06901-3431 US
- 专利权人： Purdue Pharma LP
- 当前专利权人： Purdue Pharma LP
- 当前专利权人地址： One Stamford Forum 201 Tresser Boulevard Stamford, CT 06901-3431 US
- 代理机构： Vos, Derk
- 优先权： US201261724786P 20121109; US201361788618P 20130315; US201361899002P 20131101
- 国际公布： WO2014072809 20140515
- 主分类号： C07D221/26
- IPC分类号： C07D221/26 ; A61K31/485 ; C07D401/04 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; A61P25/00 ; A61P1/00
摘要：
The present invention is directed to Benzomorphan Analog compounds of the Formula I″, Formula IA″, Formula IB″, Formula IC″, or Formula ID″ as shown below; and related Formula I′, Formula IA′, Formula IB′, Formula IC′, or Formula ID′; Formula I, Formula IA, Formula IB, Formula IC, or Formula ID; wherein R1, R2a, R2b, R3 and R4 are as defined herein. Compounds of the Invention are useful for treating pain, constipation, and other conditions modulated by activity of opioid and ORL-1 receptors.
公开/授权文献
- EP2917182A2 BENZOMORPHAN ANALOGS AND THE USE THEREOF 公开/授权日：2015-09-16
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