发明授权
EP2925857B1 USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS
有权
TRPV4拮抗剂在AMELIORATE HYDROFSALUS中的应用及相关材料和方法
- 专利标题： USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS
- 专利标题（中）： TRPV4拮抗剂在AMELIORATE HYDROFSALUS中的应用及相关材料和方法
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申请号： EP13859760.4申请日： 2013-12-03
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公开(公告)号： EP2925857B1公开(公告)日： 2018-02-14
- 发明人: GATTONE, Vincent , BLAZER-YOST, Bonnie
- 申请人： Indiana University Research and Technology Corporation
- 申请人地址： 518 Indiana Avenue Indianapolis, IN 46202 US
- 专利权人： Indiana University Research and Technology Corporation
- 当前专利权人： Indiana University Research and Technology Corporation
- 当前专利权人地址： 518 Indiana Avenue Indianapolis, IN 46202 US
- 代理机构： FRKelly
- 优先权： US201261732708P 20121203; US201361872048P 20130830
- 国际公布： WO2014089013 20140612
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; C12N5/00 ; C12N5/02 ; A61K38/00 ; A61K47/00 ; A61K31/165 ; A61P25/00 ; A61K31/00 ; A61K31/405 ; A61K31/55 ; A61K31/5377 ; A61K31/4995 ; A61K31/496 ; A61K31/495 ; A61K31/28 ; A61K31/225 ; A61K31/202 ; A61K31/18
摘要：
The present invention provides uses of TRPV4 antagonists in the treatment or prevention of hydrocephalus symptoms, also known as hydrocephaly, including hydrocephalus as a result of any structural defect, any metabolic defect, any injury (direct force to the head, indirect force to the head, shock waves, pressure changes, etc.), any insult (microbial, chemical, toxins, allergic reactions or other inflammatory process, or other pathology, eg. cancer, benign tumor, etc.). Related materials and methods are also provided herein.
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