发明公开
- 专利标题： NON-REPLICATING VIRUS-DERIVED PARTICLES AND USES THEREOF
- 专利标题（中）： 非复制，有病毒衍生的颗粒及其用途
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申请号： EP13865170.8申请日： 2013-12-20
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公开(公告)号： EP2935569A1公开(公告)日： 2015-10-28
- 发明人: CONRAD, David , BATENCHUK, Cory , LEBOEUF, Fabrice , BELL, John Cameron
- 申请人： Ottawa Hospital Research Institute
- 申请人地址： 501 Smyth Road Ottawa, Ontario K1H 8L6 CA
- 专利权人： Ottawa Hospital Research Institute
- 当前专利权人： Ottawa Hospital Research Institute
- 当前专利权人地址： 501 Smyth Road Ottawa, Ontario K1H 8L6 CA
- 代理机构： Appleyard Lees
- 优先权： US201261740856P 20121221; US201361835310P 20130614
- 国际公布： WO2014094182 20140626
- 主分类号： C12N7/06
- IPC分类号： C12N7/06 ; A61K35/76 ; A61P35/00
摘要：
There is described herein a non-replicating Rhabdovirus-derived particle that lacks the ability to spread between cells while having tropism against immortalized cells. The non-replicating Rhabdovirus-derived particle may have cytolytic tropism against immortalized cells. There is also described a non-replicating Rhabdovirus-derived particle that lacks the ability to spread between cells but has innate and/or adaptive immune-stimulating properties.
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