发明公开
EP2935616A1 PATTERN RECOGNITION RECEPTOR EXPRESSION AS A MEASURE OF SYSTEMIC HEALTH
有权
MUSTERERKENNUNGSREZEPTOREXPRESSION ALS MESSPARAMETERFÜRSYSTEMISCHE GESUNDHEIT
- 专利标题： PATTERN RECOGNITION RECEPTOR EXPRESSION AS A MEASURE OF SYSTEMIC HEALTH
- 专利标题（中）： MUSTERERKENNUNGSREZEPTOREXPRESSION ALS MESSPARAMETERFÜRSYSTEMISCHE GESUNDHEIT
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申请号： EP12816198.1申请日： 2012-12-20
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公开(公告)号： EP2935616A1公开(公告)日： 2015-10-28
- 发明人: AL-MURRANI, Samer , SCHERL, Dale S.
- 申请人： Hill's Pet Nutrition, Inc.
- 申请人地址： 400 Southwest 8th Street Topeka, KS 66603 US
- 专利权人： Hill's Pet Nutrition, Inc.
- 当前专利权人： Hill's Pet Nutrition, Inc.
- 当前专利权人地址： 400 Southwest 8th Street Topeka, KS 66603 US
- 代理机构： Daniels, Jeffrey Nicholas
- 国际公布： WO2014098865 20140626
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention encompasses methods and kits employing pattern recognition receptor expression as a measure of systemic health in a subject afflicted with an oral health condition. In particular, the present invention is directed to methods involving measurement of the expression levels of one or more Pattern Recognition Receptors including but not limited to Toll Like Receptors, myeloid differentiation primary response gene 88 (MyD88), and Nucleotide Binding oligomerization domain containing protein 1 (NOD1), in a companion animal, e.g., a dog or a cat, afflicted with an oral health condition. The described methods enable evaluation of the systemic health of the animal afflicted with an oral health condition by measuring expression levels of the indicated genes as compared to suitable controls.
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