- 专利标题: BENZAZEPINES AS SEROTONIN 5-HT2C RECEPTOR LIGANDS AND USES THEREOF
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申请号: EP13864916.5申请日: 2013-12-23
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公开(公告)号: EP2938345B1公开(公告)日: 2018-08-22
- 发明人: ROBARGE, Mike , HARRINGTON, John , GERRISH, David , MECOM, John
- 申请人: ABT Holding Company
- 申请人地址: 3201 Carnegie Avenue Cleveland, OH 44115 US
- 专利权人: ABT Holding Company
- 当前专利权人: ABT Holding Company
- 当前专利权人地址: 3201 Carnegie Avenue Cleveland, OH 44115 US
- 代理机构: Mullen, Lee Bryan
- 优先权: US201261745241P 20121221
- 国际公布: WO2014100815 20140626
- 主分类号: A61K31/55
- IPC分类号: A61K31/55 ; C07D223/32 ; C07D401/04 ; C07D417/04 ; C07D491/048 ; C07D491/052
摘要:
The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are benzazepine compounds. These compounds are serotonin receptor (5-HT2c) ligands and are useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT2c) is desired (e.g. addiction, anxiety, depression, obesity, and others).
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