发明授权
- 专利标题： IMAGE ANALYSIS FOR BREAST CANCER PROGNOSIS
- 专利标题（中）： 乳腺癌预后的图像分析
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申请号： EP13815724.3申请日： 2013-12-19
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公开(公告)号： EP2939026B1公开(公告)日： 2017-07-05
- 发明人: CHUKKA, Srinivas , SARKAR, Anindya , SCHEMP, Crystal , SERTEL, Olcay , SINGH, Shalini , TUBBS, Raymond , WARING, Paul Michael , WICK, Nikolaus
- 申请人： Ventana Medical Systems, Inc. , Cleveland Clinic Foundation , The University of Melbourne
- 申请人地址： 1910 E. Innovation Park Drive Tucson, Arizona 85755 US
- 专利权人： Ventana Medical Systems, Inc.,Cleveland Clinic Foundation,The University of Melbourne
- 当前专利权人： Ventana Medical Systems, Inc.,Cleveland Clinic Foundation,The University of Melbourne
- 当前专利权人地址： 1910 E. Innovation Park Drive Tucson, Arizona 85755 US
- 代理机构： Richardt Patentanwälte PartG mbB
- 优先权： US201261747148P 20121228
- 国际公布： WO2014102130 20140703
- 主分类号： G01N33/574
- IPC分类号： G01N33/574 ; G06F19/00
摘要：
Heterogeneity for biomarkers in a tissue sample can be calculated. A heterogeneity score can be combined with an immunohistochemistry combination score to provide breast cancer recurrence prognosis. Heterogeneity can be based on percent positivity determinations for a plurality of biomarkers according to how many cells in the sample stain positive. An immunohistochemistry combination score can be calculated. An imaging tool can support a digital pathologist workflow that includes designating fields of view in an image of the tissue sample. Based on the fields of view, a heterogeneity metric can be calculated and combined with an immunohistochemistry combination score to generate a breast cancer recurrence prognosis score.
公开/授权文献
- EP2939026A1 IMAGE ANALYSIS FOR BREAST CANCER PROGNOSIS 公开/授权日：2015-11-04
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