发明公开
EP2957558A3 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
审中-公开
细胞凋亡诱导剂用于癌症治疗和免疫球蛋白及车免疫功能紊乱
- 专利标题: APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
- 专利标题(中): 细胞凋亡诱导剂用于癌症治疗和免疫球蛋白及车免疫功能紊乱
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申请号: EP15178279.4申请日: 2011-03-10
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公开(公告)号: EP2957558A3公开(公告)日: 2016-03-02
- 发明人: DING, Hong , ELMORE, Steven , HEXAMER, Laura , KUNZER, Aaron, R. , PARK, Cheol-Min , SOUERS, Andrew, J. , SULLIVAN, Gerard , WENDT, Michael
- 申请人: AbbVie Inc.
- 申请人地址: 1 North Waukegan Road North Chicago, IL 60064 US
- 专利权人: AbbVie Inc.
- 当前专利权人: AbbVie Inc.
- 当前专利权人地址: 1 North Waukegan Road North Chicago, IL 60064 US
- 代理机构: Modiano, Micaela Nadia
- 优先权: US317575P 20100325
- 主分类号: C07C311/51
- IPC分类号: C07C311/51 ; C07D417/04 ; C07D295/112 ; C07D211/58 ; C07D295/195
摘要:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti apoptotic Bcl-2 protein.
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