- 专利标题： METHOD TO EVALUATE THE TISSUE TARGETING OF A MOLECULE OF INTEREST
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申请号： EP14706597.3申请日： 2014-02-25
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公开(公告)号： EP2959294B1公开(公告)日： 2018-08-08
- 发明人: HAMM, Grégory , STAUBER, Jonathan
- 申请人： Imabiotech
- 申请人地址： 885, avenue Eugene Avinee 59120 Loos FR
- 专利权人： Imabiotech
- 当前专利权人： Imabiotech
- 当前专利权人地址： 885, avenue Eugene Avinee 59120 Loos FR
- 代理机构： Cabinet Becker et Associés
- 优先权： EP13305211 20130225
- 国际公布： WO2014128309 20140828
- 主分类号： G01N33/50
- IPC分类号： G01N33/50
摘要：
The invention relates to a method for evaluating whether a molecule of interest binds or is incorporated in at least one target tissue, comprising visualizing and comparing the distribution of the molecule of interest and of at least one control compound within the target tissue or on the target tissue surface of at least one animal that has previously received the molecule of interest and/or the control compound. Advantageously, the distribution of the molecule of interest is visualized and compared with the distribution of positive and negative compounds using mass spectrometry imaging on the surface of the target tissue.
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