发明公开
- 专利标题: NOVEL PYRAZOLE DERIVATIVE
- 专利标题(中): 新的吡唑衍生物
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申请号: EP14756804.2申请日: 2014-02-26
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公开(公告)号: EP2963037A1公开(公告)日: 2016-01-06
- 发明人: OKANO, Akihiro , SAITOH, Fumihiko , MAKABE, Muneyoshi , OGAWA, Kouki
- 申请人: Mochida Pharmaceutical Co., Ltd.
- 申请人地址: 7 Yotsuya 1-chome Shinjuku-ku Tokyo 160-8515 JP
- 专利权人: Mochida Pharmaceutical Co., Ltd.
- 当前专利权人: Mochida Pharmaceutical Co., Ltd.
- 当前专利权人地址: 7 Yotsuya 1-chome Shinjuku-ku Tokyo 160-8515 JP
- 代理机构: Hoffmann Eitle
- 优先权: JP2013038030 20130227
- 国际公布: WO2014133046 20140904
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/444 ; A61K31/497 ; A61K31/506 ; A61K31/5377 ; A61P3/04 ; A61P25/00 ; A61P25/08 ; A61P25/14 ; A61P25/16 ; A61P25/18 ; A61P25/22 ; A61P25/24 ; A61P25/28 ; A61P25/32 ; A61P25/36 ; A61P43/00 ; C07D401/04 ; C07D417/04
摘要:
It has been desired to develop a pharmaceutical composition, which is used in agents for preventing and/or treating various diseases related to PDE10 (e.g. mental disorder and neurodegenerative disorder). The present invention provides: compounds having PDE10 inhibitory effect, in particular, compounds having a 4-heteroarylpyrazole-5-carboxylic acid amide structure represented by the following formula (I), or their pharmaceutically acceptable salts, or their solvates; pharmaceutical compositions comprising, as active ingredients, the compounds, or their pharmaceutically acceptable salts, or their solvates; and medical use of the compounds, or their pharmaceutically acceptable salts, or their solvates.
公开/授权文献
- EP2963037B1 NOVEL PYRAZOLE DERIVATIVE 公开/授权日:2019-03-27
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