发明公开
- 专利标题： CDK9 KINASE INHIBITORS
- 专利标题（中）： CDK9激酶缝边
-
申请号： EP14719457.5申请日： 2014-03-13
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公开(公告)号： EP2970268A1公开(公告)日： 2016-01-20
- 发明人: LAI, Chunqiu , MASTRACCHIO, Anthony , MIYASHIRO, Julie M. , TAO, Zhi-Fu , TONG, Yunsong , WOODS, Keith W. , PENNING, Thomas , SOUERS, Andrew J.
- 申请人： AbbVie Inc.
- 申请人地址： 1 North Waukegan Road North Chicago, IL 60064 US
- 专利权人： AbbVie Inc.
- 当前专利权人： AbbVie Inc.
- 当前专利权人地址： 1 North Waukegan Road North Chicago, IL 60064 US
- 代理机构： Modiano, Micaela Nadia
- 优先权： US201361780261P 20130313
- 国际公布： WO2014159999 20141002
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D519/00 ; C07D487/04 ; A61K31/437 ; A61K31/519 ; A61P35/00
摘要：
Disclosed are compound of Formula (Ia), wherein R
1A , R
1 , R
2 , R
10 , J, L, T, X, Y, and Z are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions, comprising one or more compounds of Formula (Ia).
1A , R
1 , R
2 , R
10 , J, L, T, X, Y, and Z are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions, comprising one or more compounds of Formula (Ia).
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