发明授权
EP2970312B1 BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME
有权
BET BROMODOMAIN抑制剂和使用其的治疗方法
- 专利标题: BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME
- 专利标题(中): BET BROMODOMAIN抑制剂和使用其的治疗方法
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申请号: EP14779458.0申请日: 2014-03-11
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公开(公告)号: EP2970312B1公开(公告)日: 2017-11-15
- 发明人: WANG, Shaomeng , RAN, Xu , ZHAO, Yujun , YANG, Chao-yie , LIU, Liu , BAI, Longchuan , MCEACHERN, Donna , STUCKEY, Jeanne , MEAGHER, Jennifer, Lynn , SUN, Duxin , LI, Xiaoqin , ZHOU, Bing , KARATAS, Hacer , LUO, Ruijuan , CHINNAIYAN, Arul , ASANGANI, Irfan, A.
- 申请人: The Regents of The University of Michigan
- 申请人地址: Office of Technology Transfer 1600 Huron Parkway, 2nd Floor Ann Arbor, MI 48109-2590 US
- 专利权人: The Regents of The University of Michigan
- 当前专利权人: The Regents of The University of Michigan
- 当前专利权人地址: Office of Technology Transfer 1600 Huron Parkway, 2nd Floor Ann Arbor, MI 48109-2590 US
- 代理机构: Clements, Andrew Russell Niel
- 优先权: US201361775886P 20130311; US201361866126P 20130815; US201461936949P 20140207
- 国际公布: WO2014164596 20141009
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; C07D413/10 ; C07D413/04 ; A61K31/4745 ; A61P35/00
摘要:
Inhibitors of BET bromodomains and compositions containing the same are disclosed. Methods of using the BET bromodomain inhibitors in the treatment of diseases and conditions wherein inhibition of BET bromodomain provides a benefit, like cancers, also are disclosed.
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